Shi Feida starred in the new short play "Clouds Going Up", which is about to go online to interpret the guardian in the Gu Wu world.

Produced jointly by Wenhuaren (Beijing) Culture Media Co., Ltd. and Fengxing Online, the highly anticipated short play "Clouds Going Up" will be officially launched on May 10th. With its unique world outlook of coexistence of ancient martial arts civilization and modern civilization, the play has attracted a large number of audiences’ attention. In this work, Shi Fei Da, a powerful actor, will play Wen Yu, the eldest brother of the three brothers and sisters of the Wen family, which has attracted strong attention from fans.

Shi Feida, who is 178cm tall and weighs 65kg, has a handsome appearance and unique temperament. He is a versatile actor with rich acting experience. As early as 2010, he partnered with Ni Ping, a famous actor and host, to host the Third China Artists Awards Ceremony in world artists association, USA, and won the Best Newcomer Award. This honor not only affirmed his hosting talent, but also predicted his infinite possibilities in the future.

While at school, he was lucky enough to participate in the film Far away Xilin Gol directed by the famous director Gao Feng, and he played Guo Qinglin (first hero), an educated youth in Beijing, and accumulated valuable performance experience. After graduation, he devoted himself to the shooting of many main melody films, constantly challenging himself and improving his acting skills.

In the anti-Japanese war film Sun Face directed by Xinyun Zhu in 2013, Shi Feida played Zhou Maosong, and his superb acting skills and solid lines were widely recognized in the industry. Whether it is the emotional expression of the role or the interpretation of the action play, he has shown excellent professionalism and acting talent.

In addition, Shi Feida’s performance in the film field is also quite eye-catching. His film works include Strange Crime, Qian Xuesen, Far-off Xilin Gol, Lost, Music and Whose Child. In these works, he created many characters with different personalities and distinct images, which showed his diversity and plasticity as an actor.

In the upcoming short play "Clouds Going Up", Shi Fei Da will play Wen Yu, the eldest brother of Wen Ji’s family, which is a role full of sense of justice and responsibility. In Yun Kaminooji, a world where ancient martial arts civilization and modern civilization coexist, he will lead his younger brothers and sisters to protect ancient martial arts civilization, maintain modern order and present a legendary heroic image for the audience.

Shi Feida said that he was very excited and looking forward to playing such a role. He believes that the story background and role setting of "Up in the Clouds" are very attractive, and he will devote himself to shaping the role and bring a brand-new and unforgettable performance to the audience. With the upcoming launch of Clouds Going Up, the audience are full of expectations for Shi Feida’s performance in the play. I believe that he will bring a double feast of vision and mind with superb acting skills and profound performance skills.

"Clouds Going Up" is not only a wonderful short play that combines ancient martial arts civilization and modern civilization, but also a masterpiece that shows the brilliance of human nature and heroic feelings. With the participation of many outstanding actors such as Shi Fei Da, the play will surely become the focus of the audience’s attention. Let’s look forward to the arrival of May 10th and witness the wonderful performance of Shi Feida in Clouds Up.

Scientists found that the smallest reptile on the earth is only 22 mm long.

  German scientists have discovered a magical chameleon subspecies in northern Madagascar. They are only the size of melon seeds and can lie on human fingers, which may be the smallest reptile on the earth.

  The Bavarian National Zoo in Munich, Germany, said that they found two adult miniature chameleons, a female and a male, in northern Madagascar. Among them, the male is only 22 mm long, which is the smallest known reptile. The other female chameleon is a little bigger, but the total length is only 29 mm.

  The researchers said that it is not clear why the species is so small, but perhaps similar to the "island effect", animals trapped on the island and with small habitats tend to evolve smaller bodies.

  However, the living environment of this new species is worrying. The habitat of this chameleon has been destroyed by deforestation. Fortunately, in recent years, the government has planned a protected area in the local area, so they are lucky to survive.

No Blowing, No Black: What about the plug-in hybrid of Volvo XC60? There is still a lot of room.

When our career is stable and our income is gradually "well-off", our originally poor life has also changed a lot, and the car we once yearned for is no longer out of reach. The late car cost of plug-in hybrid is the point that its potential consumers pay more attention to. Let’s look down with Xiaobian.

Let’s take a look at the appearance of the Volvo XC60 plug-in hybrid. The Volvo XC60 plug-in hybrid front is avant-garde and looks more delicate. Headlights are very avant-garde, and the overall look has a certain sense of hierarchy. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, automatic steering, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4708 mm * 1902 mm * 1656 mm. The car adopts sharp lines, and the side gives a very tough feeling. With large-sized thick-walled tires, smooth lines run through the whole side of the car. In the design of the rear end, the rear end looks more capable, and the taillights give people a very sharp feeling, and the shape is relatively hard.

Sitting in the car, the Volvo XC60 plug-in hybrid interior looks very comfortable, and the overall visual effect is very distinctive. The steering wheel of the car is very cute, made of leather, and the shape is very fighting. Take a look at the central control, with a 9-inch touch-sensitive LCD central control screen, which makes the interior style impressive and gives people a sense of simplicity and generosity. Finally, let’s take a look at the dashboard and seats. The car is equipped with a stylish dashboard with a sense of technology. The car adopts leather seats, and is equipped with functions such as electric adjustment with memory in the auxiliary seat, electric adjustment with memory in the seat, and seat proportion tilting, which further improves the comfort of the driver and passenger.

Next, look at the configuration. Volvo XC60 plug-in hybrid is equipped with car networking, driving mode selection, remote control key, rear wiper, traction control (ASR/TCS, etc.) and other configurations.

The moderate size of the car is a very suitable choice for many families, and the internal space is enough for daily use in families. As long as you really like it, it’s over. Go to the 4S shop and place an order.

How is China’s population data counted? These knowledge points should be understood.

  People’s Daily Online, Beijing, May 13 (Yang Xi) Recently, the release of the main data of the seventh national census has aroused great concern from all walks of life. Some netizens found that the trend reflected by the census data published this time is inconsistent with that published in non-census years, so they raised some questions about individual data.

  In this regard, the National Bureau of Statistics answered the above questions and related questions of population statistics.

  How to count and publish population data?

  At present, China’s demographic survey mainly has three ways:

  The first is the national census, which is conducted once every ten years in the year when the mantissa meets "0", and the census data is published in China Census Data.

  The second is the national 1% population sampling survey, which was conducted in the year when the mantissa met "5", and the survey data was published in the National 1% Population Sampling Survey Data.

  Third, the national sample survey of population changes, the sample size accounts for about 1&permil of the total population; In addition to the census year and the sampling year of 1% population survey, it is conducted once a year, and the survey data are published in the Statistical Yearbook of China and the Statistical Yearbook of Population and Employment of China.

  The main statistical indicators of the above three types of population data will be published in the annual data in the database of the National Bureau of Statistics.

  Why is the trend reflected by census data inconsistent with that published in non-census years?

  The population in non-census years is calculated according to the sampling survey data of that year. Due to the missing rate of sampling surveys in some years, there will be some deviations in the estimated population as a whole, and these deviations will continue to accumulate with the passage of time.

  Carrying out the population census once every 10 years can comprehensively find out the number, structure and distribution of China’s population, let us know more clearly the development of China’s population in the past 10 years, and provide extremely valuable data for better studying population issues and formulating population-related policies.

  So how to deal with this inconsistency? According to international practice and common practice, after the census, the annual data published between the two censuses are generally revised according to the census results, so as to reflect the population development track more truly and objectively. In the sixth national census and the just-concluded fourth national economic census, historical data were also revised according to census data. At present, this work is in progress, and the relevant data will be released on schedule after the revision is completed.

  Is the population statistics based on household registration or residence?

  At present, China’s population census and population survey are counted and summarized according to the resident population. The time standard for judging the permanent population is half a year, and the space standard is township, town and street.

  The resident population is an important basic data for formulating the national economic and social development plan, evaluating the national economic production capacity, and evaluating the welfare level of residents. It has a wide range of applications, such as financial expenditure, urban construction, housing construction, allocation of public facilities, education investment, medical investment and public utility investment, etc., which need to be planned according to the size of the resident population.

  The registered population refers to the registered population in a certain area, regardless of whether they go out or not, as long as they register their permanent residence in the public security household registration management department. The data of registered population is counted by the public security department. For a long time, China has established a set of perfect household registration statistics and management system, which has played an important role in social management.

  How is the floating population data counted?

  Floating population refers to the population whose residence is inconsistent with the township street where the household registration place is located, and who has been separated from the household registration place for half a year or more (excluding the separation of households within the municipal area). The survey indicators used to judge and reflect the floating population include: the place of registration, the place of residence at the time of investigation, the time of leaving the place of registration and the reasons for leaving the place of registration. The National Bureau of Statistics formulates a demographic survey system according to the Statistics Law of the People’s Republic of China, conducts demographic surveys on a regular basis, and publishes major demographic data such as permanent population, birth population, dead population, urban and rural population and floating population.

Connect Tianshui’s innovative dish "Gansu Mala Tang" to the whole country.

  Line up for spicy food.

  Tempting Gansu mala Tang.

  "Bouquets of vegetables" are one after another, and enthusiastic diners are one after another. After Tianshui Mala Tang went out of the circle, this "sky-splashing flow" also began to flock to Lanzhou, and the passenger flow of major Mala Tang shops in the city continued to rise obviously. Embracing this wave of traffic dividends, on March 20th, famous local restaurants in Lanzhou took advantage of the situation to offer a new "Gansu Mala Tang" and add another fire with innovative dishes. Even the University of Science and Technology Beijing, thousands of miles away, issued an official announcement, "The campus canteen window, authentic Tianshui Mala Tang in Gansu, is officially launched"!

  A Lanzhou hot spicy dip famous store huo Shang Jia huo

  When visiting Lanzhou, Jin Lan Mala Tang in Anning District must be on the must-eat list.

  At noon on March 19, looking at the endless diners, Ms. Chen, a citizen of Lanzhou, lamented: "Jin Lan Mala Tang, which is deeply loved on weekdays, has become more popular recently!" This is an old-fashioned Mala Tang shop in Lanzhou. The proprietress’s name is Wen Jinlan, and she is from Longnan, Gansu Province. She has been here for more than 20 years. After the hot spicy dip in Tianshui, more and more diners came here, and sometimes they even had to wait in line for an hour to eat.

  In order to meet the huge passenger flow, it is normal for Wen Jinlan to get up early for nearly 20 hours every day. The reason why it is popular, in the view of the proprietress Wen Jinlan, is because of "popular taste, everyone likes it". The raw materials such as Gangu pepper, Wudu Dahongpao pepper, vermicelli specially customized from Dingxi and grain vinegar produced nearby have jointly contributed to the mouth-watering "spicy and hot".

  "A large pot of vegetables, all kinds of ingredients wrapped in red juice, a spoonful of crisp sour radish, and the smell of oily spicy seeds between chopsticks directly hit the taste buds." Every meal, Yanji Mala Tang in Zhengning Road, Chengguan District, all the tables inside and outside the store are full. Many people ask, after more than 30 years of opening, people are so popular that there must be an exclusive secret recipe, right? Mr. Zeng, the boss, said frankly: "My wife and I are out-and-out Jianyang people in Sichuan. We have lived in Lanzhou for decades. We improved and adjusted the proportion of juice according to the tastes of local people, which reduced the hemp degree of pepper. It brings together Gansu local materials such as Dingxi Kuanfen and Gangu Chili, forming a unique flavor of Gansu Mala Tang. "

  B Lanzhou local catering enterprises innovate dishes.

  On March 20th, Duanji Hotel in Yantan, Lanzhou officially launched the new dish "Gansu Mala Tang". Yang Guoyan, Chairman of the Folk Food Committee of Longcai Association and Deputy General Manager of Lanzhou Duanji Catering Management Co., Ltd., told Benben News reporter: "In order to meet this wave of traffic, we have developed a new dish close to Tianshui Mala Tang, with ingredients such as Gangu Chili, Dingxi Kuanfen and Qin ‘an Zanthoxylum. As a Longcai hotel, our goal is to create a ‘ Ganwei hot spicy dip ’ The alternative ingredients will be more extensive, adding lily, yak meat and so on. " Yang Guoyan said that many employees in the store are from Tianshui. Through repeated trial production for many days, this new product has been officially launched.

  "After Tianshui Mala Tang is on fire, how can we seize this wave of traffic and continue to undertake this heat to Lanzhou? In fact, we still have to work hard on product innovation." Yang Guoyan said, "Gansu is more delicious than mala Tang, Wuwei ‘ Three sets of cars ’ , Zhang Ye ‘ Stir-fry firecrackers ’ , Longnan stirred up the group … … Longshang cuisine has a long history. How to make use of this mala Tang craze to make all kinds of snacks in Gansu known to more people and promote them to the whole country requires not only the help of the cultural tourism department, but also the joint efforts of the catering industry and other departments. "

  C "Gansu Mala Tang" online orders skyrocketed.

  According to the data of Meituan, since March, the search volume of keywords related to "Gansu Mala Tang" has increased by 18.5 times from last month, and the number of public comments has soared by 13.2 times. The take-away orders of Gansu Mala Tang increased 66 times from last month. Beijing, Xi ‘an, Jinan, Shanghai and Tianjin are the top five cities in search volume.

  At the same time, the popularity of Tianshui Mala Tang has also driven the growth of local cultural tourism consumption. The booking volume of travel orders in Tianshui City, Gansu Province increased by 71.8% compared with the same period of last year. Among them, the order volume of hotels and homestays increased by 73.6% year-on-year, and the order volume related to scenic spots increased by 216.8% year-on-year. Maijishan Grottoes, Fuxi Temple, Maijishan Hot Springs, Xianrenya and Yuquan Temple are the top five scenic spots in terms of order volume. Shaanxi, Henan, Jiangsu, Guangdong, Ningxia, Beijing and Sichuan are the top provinces and cities in the source of off-site orders.

  On various social platforms, many netizens called for authentic Gansu Mala Tang to be eaten in their hometown, and called on Tianshui people to open stores in their hometown. Some physical stores that see business opportunities are trying to seize the opportunity … …

  Gansu Beijing Office, located in Beijing Feitian Mansion, has recently put up "Gansu Mala Tang", attracting many netizens to taste the punch card. And a female shopkeeper from Tianshui also decided to open a Gansu Mala Tang restaurant in Sanlitun, one of the hottest business districts in Beijing, which is expected to be officially opened in half a month.

  On March 19th, University of Science and Technology Beijing issued a document saying that "Gansu Tianshui Mala Tang" will be launched in the school cafeteria at noon. In order to reflect the authenticity, the school emphasized that "soul juice" is all from Gansu, and it brings together two ingredients of Tianshui, namely Gangu pepper and Qin ‘an pepper. The potato powder is elastic and smooth, Gangu chili pepper is full of oil, and the most delicious thing is the intersection of fresh hemp and Qin ‘an pepper. In fact, as early as 2012, the school established a fixed-point assistance relationship with Qin ‘an County, Gansu Province, and purchased Qin ‘an pepper every year. This year, a new potato powder procurement project was added, and the canteen master went to the local area for research and study, bringing students a better experience.

  Searching with "Gansu Mala Tang" as the key word through Tianyanchao platform, in the past three months, there have been more than 200 new Mala Tang shops in China. Among them, since February this year, there have been more than 150 newly opened Gansu Mala Tang shops in China. According to the data of Tianyancha Professional Edition, up to now, there are more than 9,600 mala Tang related enterprises in Gansu, while there are nearly 900 related enterprises in Tianshui City alone.

  Text/Figure Benliu News Lanzhou Morning News reporter Xu Jingwen

Opinions of Beijing Municipal People’s Government on Doing a Good Job in Promoting Employment at Present and in the Future

Jing Zheng Fa [2018] No.30

District People’s governments, municipal government commissions, offices and bureaus, and municipal institutions:

  In order to thoroughly implement the Supreme Leader’s Socialism with Chinese characteristics Thought in the New Era and the spirit of the 19th National Congress of the Communist Party of China, fully implement the decision-making arrangements of the CPC Central Committee and the State Council on stabilizing employment, take multiple measures simultaneously and comprehensively, and ensure the smooth completion of the employment objectives and tasks in this city and the sustained and stable employment situation in the current and future period, according to the spirit of "Several Opinions of the State Council on Doing a Good Job in Promoting Employment in the Current and Future Period" (Guo Fa [2018] No.39), combined with the actual situation, the following implementation opinions are put forward:

  First, support the stable development of enterprises

  (1) Increase the support for stabilizing posts. Since January 1, 2019, 50% of the unemployment insurance premium actually paid in the previous year can be returned to the insured enterprises that have not laid off employees or laid off fewer employees. From January 1 to December 31, 2019, for the insured enterprises that face temporary production and operation difficulties and are expected to recover, and insist on not laying off employees or reducing layoffs, the return standard can be determined according to the monthly per capita unemployment insurance premium and the number of insured employees in the previous year of this city for six months.

  (2) Continuously optimize financial services. Improve the policy financing guarantee system, increase the scale of financing guarantee for small and micro enterprises, guide more financial resources to support entrepreneurial employment, and further alleviate the problem of financing difficulties for small and micro enterprises. Banks and other institutions that have made outstanding achievements in the work of business guarantee loans may be rewarded according to 1% of the newly issued business guarantee loans in that year.

  (3) Guiding and stabilizing labor relations. Strengthen the supervision and management of enterprises’ implementation of the labor contract system and the collective contract system, encourage enterprises to carry out collective consultations with employees, urge enterprises to protect the legitimate rights and interests of employees according to law, further build harmonious labor relations and stabilize employment.

  Second, encourage entrepreneurship to drive employment

  (four) increase the support for the discount of business guarantee loans. Small and micro enterprises registered and operated in this city, when the number of newly recruited people who meet the application conditions for business start-up guarantee loans reached 25% of the existing employees (15% for enterprises with more than 100 employees) and signed labor contracts with them for more than one year, can apply for business start-up guarantee loans with a maximum of 3 million yuan according to the standards of the number of recruited people and the amount of each person not exceeding 150,000 yuan, and the discount funds will be borne by the finance. Increase the maximum amount of personal small convenient loans from 100,000 yuan to 150,000 yuan.

  (5) Strengthen the construction of entrepreneurial carriers. Accelerate the construction of business incubation carriers for key groups and provide low-cost venue support, guidance services and policy support for entrepreneurs; According to the number of entities, the incubation effect and the employment effect, the business incubation base will be rewarded. Support areas with stable employment pressure to provide free business venues for unemployed people to start their own businesses. Strengthen the construction of the "Growth Enterprise Market for College Students" in this city’s regional equity market, and provide professional services such as project incubation, capital docking, equity custody, training and guidance for entrepreneurial enterprises.

  Third, carry out skills training to improve the quality of employment

  (six) support enterprises in difficulty to carry out skills training for employees. From January 1 to December 31, 2019, difficult enterprises can use the education funds of enterprise employees to carry out on-the-job training for employees by themselves or by entrusting institutions with corresponding training qualifications in this city. Employees who have obtained corresponding vocational qualification certificates or vocational skill grade certificates after training shall be subsidized by their enterprises according to 50% of the subsidy standard for technical skill upgrading; To carry out non-level skills training and each person’s training time is not less than 20 class hours, and give enterprise subsidies according to the standard of 500 yuan per person.

  (seven) to encourage workers to improve their professional skills. From January 1, 2019 to December 31, 2020, the application conditions for technical skills upgrading subsidies in this city were relaxed from employees of enterprises who participated in unemployment insurance for more than 3 years to those who participated in insurance for more than 1 year; Persons with employment difficulties in urban and rural areas in this city who have not received unemployment insurance benefits can enjoy cost of living allowance, which is not less than that in 35 yuan, per person per day during the training period, and cost of living allowance policy only enjoys it once per person per year.

  (eight) to mobilize social forces to participate in vocational training. Support all kinds of vocational colleges (including technical colleges), ordinary colleges and universities, vocational training institutions and qualified enterprises to undertake vocational skills training or entrepreneurship training for unemployed people and rural migrant workers, and give vocational training subsidies according to regulations. The subsidy standard is determined according to the training cost, training duration, market demand and obtaining relevant certificates. Timely study, adjust and enrich the catalogue of vocational training subsidies, and expand the benefits of policies.

  Fourth, accurate policy to help employment

  (nine) to expand the scope of employment trainee subsidies. From January 1, 2019, the scope of employment trainee subsidies will be expanded from unemployed college graduates who have left school to registered unemployed people aged 16-24 and rural laborers who have transferred employment registration; Organize them to participate in employment internships for no more than 12 months, give employment internship subsidies according to regulations, and appropriately raise the subsidy standards.

  (ten) to improve the employer’s post subsidy standards. Employers will be encouraged to recruit people with employment difficulties in urban and rural areas, retired soldiers and laid-off workers from enterprises, and the post subsidy standard will be raised from 5,000 yuan per person per year to 8,000 yuan per person per year.

  (eleven) to promote the employment of rural labor. Vigorously develop industrial projects with quick results and high returns to help rural laborers find jobs nearby. Encourage outstanding young people to return to their hometowns to start businesses and promote farmers’ employment. Broaden the channels for rural labor to transfer employment, support rural labor who are willing to go out for employment in urban public service posts, and implement relevant policies such as post subsidies and social insurance subsidies. Give full play to the role of rural public welfare posts and enhance the ability to provide care for rural people with employment difficulties.

  V. Optimizing services to boost employment

  (twelve) the implementation of permanent service. Unemployed people in this city and rural laborers who require the transfer of employment can apply for unemployment registration, transfer of employment registration and other businesses in the social security offices in the streets (towns) of their permanent residence, enjoy employment and entrepreneurship services nearby, and apply for employment and entrepreneurship support policies at the municipal level and in the districts where their permanent residence is located. People with employment difficulties in urban and rural areas can receive employment assistance in their permanent residence.

  (13) Improve service quality. Actively use the "internet plus" model, build a network service platform for employment and entrepreneurship, promote departmental information sharing, streamline work links, and reduce application materials, so that "information runs more and people run less errands". Actively carry out policy propaganda, announce the policy list, bidding process, subsidy standard, service organization and contact information, supervise the complaint telephone number to the society, go deep into enterprises to preach policies, understand difficulties, solve problems, do a good job of helping, and promote the implementation of various employment policies and services.

  (fourteen) to ensure the basic livelihood of the people in need. We will fully implement the unemployment insurance system and steadily raise the level of unemployment insurance benefits. A temporary living allowance of 3,000 yuan will be given to registered unemployed people who have difficulties in life and do not meet the conditions for receiving unemployment insurance benefits. We will integrate urban subsistence allowances, rural subsistence allowances, and low-income family identification systems, expand the scope of assistance, lower the threshold for assistance, and timely include families that meet the minimum living guarantee conditions into the minimum living guarantee scope. Improve the city’s temporary assistance system, give temporary assistance to qualified personnel, and help people in need to get out of trouble.

  Sixth, improve the safeguard mechanism

  (15) Strengthen organizational leadership. Give full play to the role of the municipal social security and employment work leading group, improve the working mechanism, and make overall plans for the analysis, policy formulation, guidance and inspection of the city’s employment situation. The relevant municipal departments and district governments should earnestly assume the main responsibility of promoting employment, strengthen communication and close cooperation, and do their best to promote employment.

  (sixteen) to strengthen publicity and guidance. Guide enterprises to stabilize employees’ employment through transformation, training and job transfer, and support "double innovation"; Guide workers to establish a correct concept of employment, actively improve their employment skills, and realize employment and entrepreneurship through their own efforts. It is necessary to mobilize the forces of all sectors of society to form a joint force to promote employment.

  (seventeen) optimize the financial security. Comprehensively sort out the existing capital projects that guarantee basic living, promote employment and stabilize employment, and on the basis of maintaining policy continuity and stability, merge and simplify the capital projects and use methods to improve the efficiency of capital use. Strictly implement the real-name management of employment assistance targets and effectively ensure the safe operation of funds.

the people’s government of beijing city

December 20, 2018

Omicron iterates fast, can COVID-19 vaccine market learn from the "flu model"

BA.4 and BA.5, the new branches of Omicron with stronger communication power, have recently attracted attention. The new branch has triggered a new infection peak in South Africa, and the Portuguese National Institute of Health also estimates that its growth advantage is 13% more than that of BA.2.

Screenshots from the nextstrain website show that the different Omicron branches represented by yellow, orange and red are iterating rapidly within half a year, and the new branches represented by orange and red are also expanding in the cracks.

Screenshot of nextstrain website. According to the uploaded sequencing data, since December last year, the mainstream branches in Omicron have gradually changed from BA.1 (shown as 21K) to BA.2 (shown as 21L) to BA2.12.1 (shown as 22C), and the area occupied by new branches is also expanding.

The new branches of Omicron are frequent. Is the current COVID-19 vaccine still effective? Do the branches BA.2 and BA.5 need their own vaccines? Should the update of COVID-19 vaccine keep up with the variation of virus? How to keep up with the virus mutation? With the above questions, the reporter of Science and Technology Daily contacted and interviewed a number of industry experts.

Is the current vaccine still effective?

Does the mutation branch in Omicron constantly trigger new infection peaks, which means that the current COVID-19 vaccine will be invalid?

Authoritative experts in the industry responded to the Science and Technology Daily reporter and said: "Current vaccines can still provide the most basic protection in ensuring the reduction of severe illness and death.. The epidemic in COVID-19 has been going on for two and a half years. At present, it seems that there is no possibility for Covid-19 to achieve zero infection through vaccination. COVID-19 vaccine can ensure the effect of reducing infection and avoiding serious illness and death. "

Regarding the role of the current vaccine in epidemic prevention and control, the person in charge of vaccine-related production enterprises in COVID-19 holds the same view: "The existing vaccine is no problem in preventing severe illness and death at present, but it will not be 100% anti-infection."

Many statistics or research results from the real world show that the current vaccine plays a significant role in preventing severe illness and death. For example, the latest data in Hong Kong (as of May 25th) showed that the mortality rate of those infected in Omicron who were not vaccinated was 3.04%, while the mortality rate of those infected with three doses of vaccine dropped significantly to 0.04%.

Do the branches BA.2 and BA.5 all need their own vaccines?

According to WHO’s latest weekly report on epidemiological progress in COVID-19 (May 25th),Omicron BA.2 and its progeny pedigree (BA.2.X) have become the main popular variants in the world.At present, the relative proportions of BA.2.X, BA.4 and BA.5 are 94%, 0.8% and 1% respectively.

This shows that during the evolution of Omicron mutant, the branch BA.1 is disappearing. However, the reporter learned that at present, most vaccines against Omicron in China are designed and developed for BA.1.

Whether it is necessary to develop new vaccines for new branches, the industry generally judges from the perspective of vaccine protection: if the activity of neutralizing antibodies produced by the original vaccines against mutant strains is greatly reduced, it is necessary to develop new vaccines; If it still has a good neutralizing effect on the mutant, there is no need to develop a new vaccine.

Although Omicron strain mutates rapidly and different branches appear, butNew vaccines will not be introduced for each branch, and there is no need to do so.. Relevant experts reminded: "If you continue to monitor, you will find that many mutations will disappear soon."

Can vaccine update keep up with virus iteration?

In the technical route of vaccine development in COVID-19, the design cycle of mRNA vaccine is short. On the basis of a mature platform, the design can be completed within 7 days, and the preclinical trials including animal experiments can be completed in about one month.

Industry experts engaged in the research and development of mRNA vaccine said that for the variant branch, the mRNA vaccine does not need to obtain the strain, but only needs to optimize the vaccine sequence according to the variant sequence and test the expression efficiency, and then pre-clinical trials can be carried out. Covid-19 Omicron mutant mRNA vaccine, developed by Suzhou Aibo Bio, China, has been approved for clinical research in UAE.

In response to virus variation, the technical route of inactivated vaccine can also complete the preclinical study of new strains in a short time by establishing an emergency system. The reporter previously learned that it can be advanced to the clinical trial application stage about 2 months after obtaining the new strain.

Keep up with the variation, can COVID-19’s vaccine market learn from the "flu model"

In order to cope with the frequent mutation of viruses, there are precedents for vaccine updates to follow closely. For example, the influenza virus vaccine is recommended by WHO every year, and countries produce new influenza vaccines accordingly.

In order to keep up with the variation in Covid-19, can the "flu model" be used for reference in the marketing of vaccines in COVID-19?

It is estimated that the future development of COVID-19 vaccine needs to adopt the influenza model.The authoritative experts mentioned above responded, but WHO is unable to recommend mainstream strains through monitoring now, because the pandemic is not over yet.

Another advantage of the "flu model" is that it greatly shortens the time to market for new vaccines. Because there is no need for re-approval, its batch issuance system can effectively shorten the period from vaccine development to marketing. Experts in the industry said that after polishing and construction, various technical routes and platforms have gradually matured, the research and development speed has been accelerated, and the production process has been stable.If the "flu model" can be adopted in the development and marketing of vaccines in COVID-19, the time to market for new vaccines will be greatly shortened.

WHO has revealed some unexpected phenomena in its weekly epidemiological report: available data show that BA.4, BA.5 and BA.2.12.1 spread faster in countries where BA.1 was once prevalent, but less in countries where BA.2 was prevalent; The vaccination degree of each country may have an impact on the popularity of the new branch of Omicron. Visible,Covid-19 mutation and vaccine immunogenicity are mutually causal and widely related, and updating the vaccine in time may have an impact on virus mutation.

Source: Science and Technology Daily

Original title: "Omicron iterates fast, is it necessary to be" anxious "about the vaccine? 》

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National Health Commission: We will summarize the experience of "sharing nurses" and guide the standardized development.

  Yangguang. com BeijingsixmoonfiveJapan News (Reporter Sun Bingjie) Recently, a new type of Internet has emerged in Shandong and Fujian.+Home-based medical model-"shared nurses" has aroused public discussion. This one is connected to the Internet.+The new medical model of hitchhiking not only brings convenience to patients, but also causes social doubts about its safety. National Health Commission, as the competent department, responded a few days ago and will summarize the experience of "sharing nurses" in various places to guide the standardized development.

  "shared nurses": a win-win situation for nurses and patients?

  Bike-sharing, familiar with the public, etc.APPSimilarly, turn on the phone.APPChoose the service you need, place an order, wait for the platform to screen, and you can enjoy the services provided by nurses or doctors in just ten minutes. This is a "shared nurse" model popular in Jinan, Shandong and other places recently.

  "shared nurse"APPWhat services can you provide? The reporter downloaded an earlier one with the words "shared nurse" on the mobile phone.APPBesides routine injections, infusions, blood collection, etc., its homepage can also provide services such as catheterization, enema, stitches removal and maternal and child care.

  

  This new type of "Internet"+The mode of "home care" is being welcomed by many users, such as Ms. Wan Juan in Beijing.APPA loyal user of. She told reporters that her family is old and young, and she rarely has time to go to the hospital.APPSolved her "trouble" to a great extent. "I have to queue up when I go to the hospital to register. The elderly and children at home are uncomfortable. I now make an appointment with doctors and nurses directly."

  At present, the shared nurses launched by various platformsappThere is little difference in functions, mainly providing on-site service for nurses. In addition to the top three hospitals, some nurses come from outpatient departments of primary hospitals. The service items are varied, but mainly include injection and infusion, dressing change and maternal and child care.

  Compared with public hospitals, the reporter noticed that nurses were shared.APPIt is generally expensive in price. Take basic services such as infusion and injection as an example. Most of themAPPOn-site service price is at150About yuan, more than hourly billing. According to the price of medical services in public hospitals in Beijing(2017edition),Adult outpatient intravenous infusion general public hospital price insevenYuan or so, only this one is close.twentyTimes.

  However, in the view of employee Zhao Fei, the current pricing is still in the "acceptable range" compared with the cost of patients queuing in the hospital. And the shared nurse model can not only provide convenience for patients, but also give patients and nurses appropriate subsidies, which can increase the income of nurses.

  "Now nurses pay more, but their income is not ideal. In particular, some nurses are too old to work at night, and theseAPPIt provides them with opportunities to realize their skills and increase their income. Yang Jie, a nurse in a hospital in Xicheng District, Beijing, told reporters.

  "Aging" gives birth to the demand for home care

  In fact, shared nursesAPPIt is not the first time that it has appeared. The upsurge of sharing economy in recent two years has also made the medical field the next outlet. Huge nursing demand and professional nursing force through "Internet"+"Shared nurses" are entering the families of ordinary people.

  The latest statistics of the National Office for Ageing, as of2017At the end of 2008, the whole country60The number of elderly people over the age of2.4Billion, accounting for the proportion of the total population.17.3%, average nearfourIndividual labor supportoneAn old man. Many elderly people suffer from chronic diseases and need regular health care; Among the hospitalized patients, at least20%~30%% of patients still need nursing after discharge.

  There is a strong demand for nurses’ home service. Mobile nursing platform provides opportunities for nurses to realize their skills. While "shared nurses" seem to be "win-win", the unsafe factors can not be ignored, mainly focusing on nurse qualifications, medical safety and so on.

  According to National Health Commission2008The Measures for the Administration of Nurses’ Professional Registration, which was implemented in, stipulates that nurses can only engage in nursing work according to the registered practice place after obtaining the Nurse’s Practice Certificate through practice registration. According to the reporter’s understanding from National Health Commission, at present, except for Beijing, Tianjin and Guangdong, which are pilot areas for regional registration of nurses, nurses in most other provinces have no multi-point qualification.

  "This means that the on-site service is actually carried out outside the registered practice place and is suspected of illegal practice." Analysis of Zhou Xuefeng, a lawyer of Beijing Jingshi Law Firm.

  In addition, how to avoid the medical risks in the nurse’s home service center? It is the key to whether the "shared nurse" platform is reliable. The reporter noticed that the current shared nursesAPPFor patients with higher risks, they will generally not take orders, and nurses will also choose orders with lower risks. Yang Jie, who has many years of nursing experience, admits that the biggest risk of door-to-door infusion lies in its uncontrollable nature, and patients may have adverse reactions during infusion. The patients’ families lack emergency rescue equipment, "not only the patients will be very dangerous, but also the disputes between doctors and patients will be difficult to sort out."

  Relevant policies are on the way.

  this yearfourmoon28On April 20, the General Office of the State Council officially released "On Promoting the Internet"+Opinions on the development of medical health. Require a sound "Internet"+Medical health "service system. Promote the integration of Internet and medical and health services from the aspects of medical treatment, public health, family doctor signing, drug supply guarantee, medical insurance settlement, medical education, popular science and artificial intelligence application. It covers many aspects of medical treatment, medicine and medical insurance.

  In an interview with a reporter from the Central Broadcasting Bureau, the relevant departments of National Health Commission pointed out that some provinces and cities with conditions have explored the "shared nurse" door-to-door service, which has solved the problem of the elderly and patients with mobility difficulties, brought convenience to the people, and is an exploration of nursing service entering the family.

  According to the forecast of the World Health Organization,2050In, China will have.35%The population of more than60Years old, which means that China is also facing strong aging pressure under the background of building a well-off society in an all-round way. In Zhao Fei’s view, aging+The limited medical resources have created many urgent needs for Chinese to see a doctor at home. "Although the’ shared nurse’ has some flaws, it has responded to some extent.The basic desire of "seeing a doctor at home". Wu Zhipan, a professor at Peking University, said, "Most norm makers are facing the Internet.+"Mode, it is inevitable to behave behind some, should set aside time. "

  Regarding whether it is legal for nurses to sign contracts with the online platform, the relevant authorities said in an interview that the multi-point practice of signing online platforms and physical medical institutions is not the same, but there is no relevant policy. National Health Commission said that the next step will be to gradually revise and improve the policies related to nurse practice management on the basis of summing up the pilot experience, combining with the promotion of graded diagnosis and treatment and the continuous deepening of medical reform. At the same time, further implement the "General Office of the State Council on promoting the Internet"+Opinions on the development of medical health, combined with the experience of exploring and developing "shared nurses" in various places, guides standardized development to meet the diversified and multi-level health needs of the public.

Ministry of Human Resources and Social Security: Strive to create diversified employment opportunities and do everything possible to create conditions for youth employment and entrepreneurship.

  Cctv newsToday (August 30th), Zhang Ying, director of the Employment Promotion Department of the Ministry of Human Resources and Social Security, answered a reporter’s question about youth employment at a policy briefing in the State Council, saying that young people are the most active and dynamic force in the whole society, and there is great potential for innovation and creation. Promoting youth employment is related to the improvement of people’s livelihood, high-quality development and the future of the country. The 14th Five-Year Plan for Employment Promotion not only emphasizes the continuous employment of college graduates, but also clearly puts forward the promotion of youth employment for the first time and makes separate arrangements.

  Zhang Ying said that the overall consideration is to promote youth employment and entrepreneurship through multiple channels through the efforts of the supply and demand sides and the support of policy services. The specific measures are as follows:

  First, focus on creating diversified employment opportunities.Expand employment and entrepreneurship opportunities in new industries, new formats and new modes, connect with the optimized industrial layout, coordinated regional development and the talent demand of enterprises in key industries, improve the demand forecasting, factor allocation and coordinated development mechanism of human resources, and support young people to find jobs and start businesses in areas that are in urgent need.

  The second is to enhance the ability of career development.Improve the job-seeking ability through career guidance, increase the guidance of career planning, career experience and job-seeking methods, and enhance the adaptability of young people in the workplace. Through vocational training, improve professional skills, expand special ability training, new vocational training, and replace training with work to enhance the growth of youth employment. Increase practical experience through employment internship, provide more internship opportunities for management and technical positions, and enhance the post competence of young people.

  The third is to focus on enhancing the pertinence of employment services.We will improve the employment service model that meets the needs of young people, and provide employment services such as job introduction according to their employment wishes, so as to improve their accuracy in choosing jobs. Open the channels of information services, organize professional and professional recruitment activities, combine online and offline, and innovate more employment service models such as "live broadcast with posts" that meet the characteristics of young people.

  The fourth is to focus on helping the difficulties.We will implement the youth employment sailing plan, provide practical guidance, classified guidance and follow-up assistance to unemployed young people, and guide them to stand on their own feet and enter the market and integrate into society. At the same time, we will provide employment assistance to some unemployed young people who are in difficulty and secure the bottom line of employment.

  College graduates have always been the most important among the youth groups. For recent college graduates, the Plan has defined a special employment and entrepreneurship support plan to continuously expand market-oriented and socialized employment channels. For previous unemployed graduates, they can also get better support through relevant measures and arrangements to promote youth employment.

  Zhang Ying said, we will do our best to create conditions for young people to find jobs and start businesses, and help them contribute to the country with their wisdom and talents, so as to forge ahead and serve the society.

Mary said that the Spring Festival Evening was like an exam, and Zhang Yimou was like a god to himself.

On February 9th, Mary, the actor who made his eighth appearance on the stage of the Spring Festival Evening, came to the interview room. She said that every time she comes to the Spring Festival Gala, like the exam, she is particularly nervous and under great pressure. When she has good works, she will be more confident in acting, but this year’s time is relatively hasty.

Mary said that it is actually more difficult for an actress to act in comedy than an actor, because she is not willing to "sell" or "play", but rather wants to start from the characters, so whether it is the structure or the character of the role, it is still more challenging to act.

Talking about the upcoming film Article 20, Mary said that he didn’t expect to cooperate with director Zhang Yimou one day. From the day he joined the group, he felt that everything was like a dream. Mary also said that Zhang Yimou’s state of filming on the spot, his unique ideas, his requirements for actors and his control of all the plays made him feel that the director is the most attractive and soul person in the crew and the soul of a movie. "I think the director is like a god to me."

Recalling that in 2023, Mary admitted that he was a model worker. Last year, there were 3 or 4 films and played some very powerful female roles. The creative process was happy, but it was also very painful. The result was very satisfactory for himself. I hope I can give myself a holiday in the new year.

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